Brain Ultimate TMS
The Most Advanced Affordable TMS System for Your Practice
Elevate your clinic with Brain Ultimate TMS — the only system with deionized water cooling for true 24/7 operation, multiple FDA-cleared protocols, and cloud-connected treatment management.
FDA-Cleared Treatment Protocols
Choose the protocol that best fits your patients' needs
Standard MDD Protocol
Proven efficacy for Major Depressive Disorder with established clinical outcomes across 50+ active clinics.
FDA CLEAREDiTBS Protocol
Accelerated intermittent theta burst stimulation — clinically equivalent outcomes in a fraction of the time.
FDA CLEAREDEnhanced MDD Protocol
Extended protocol for optimized patient comfort with flexible treatment scheduling.
FDA CLEAREDOCD Protocol
Specialized treatment targeting the anterior cingulate cortex for Obsessive-Compulsive Disorder.
FDA CLEAREDThe Future of Neuromodulation
Experience the most advanced affordable TMS system designed for continuous operation and clinical excellence.
Only Deionized Water Cooling
The only TMS system using pure deionized water — enabling true 24/7 continuous operation without overheating. Maximize patient throughput and clinic efficiency.
Intelligent System Monitoring
Real-time monitoring of temperature, coolant circulation, and system status with automatic warning at 41°C and safety auto-stop at 42°C.
Precision Targeting
Advanced coil positioning with 10-20 system caps and neuronavigation compatibility for accurate, reproducible stimulation delivery.
Complete Ecosystem Integration
Compatible with EEG, MEP monitoring, and neuronavigation systems — plus cloud connectivity for centralized treatment management.
Complete Neurophysiology Solutions
70+ years of Italian excellence — now part of the Brain Ultimate family
Introducing Our EB Neuro Division
Brain Ultimate brings the complete EB Neuro portfolio of neurophysiology equipment to North America. From routine EEG to advanced EMG/EP and critical care monitoring, discover FDA-cleared solutions trusted in over 50 countries worldwide.
Who We Are
Brain Ultimate is advancing the standard of non-invasive neuromodulation technology. We combine innovation, safety, and clinical evidence to deliver TMS solutions that make a real difference for practices and patients.
Our proprietary liquid-cooling system uses pure deionized water — the only TMS technology of its kind — enabling true 24/7 continuous operation. This integrated approach brings together intelligent temperature control, high-conductance liquid-cooled coils, and robust power delivery to eliminate the overheating constraints that limit competing devices.
With 176 peer-reviewed publications, over 5,000 study participants, and an average impact factor of 10.7, our research foundation is among the strongest in the TMS industry. In collaboration with Shenzhen Yingchi Technology Co., Ltd. — our manufacturing partner — and EB Neuro, our sister company in neurophysiology, we bring a comprehensive neuromodulation and neurophysiology ecosystem to the North American market.
Why Our Liquid Cooling System Stands Out
The only TMS system using deionized water for true 24/7 operation
24/7 Continuous Operation
Proprietary deionized water cooling enables non-stop operation — setting a new industry standard for patient throughput and clinic efficiency.
Superior Safety Profile
Pure deionized water eliminates the risks associated with transformer oil cooling systems used by competitors, providing a cleaner treatment environment.
Exceptional Durability
Resistant to electrolysis, corrosion, and blockages. Most clinics operate 2–3 years between coolant service, with minimal maintenance required.
Intelligent Monitoring
Real-time temperature tracking with automatic warning at 41°C and safety auto-stop at 42°C, ensuring optimal performance at all times.
Brain Ultimate Cloud
Streamline your practice with secure, cloud-connected treatment management across all your TMS devices.
Additional devices +$75/month each.
Ready to Transform Your Practice?
Join the 50+ clinics nationwide that trust Brain Ultimate for reliable, affordable, and advanced neuromodulation solutions — with no per-pulse fees and true 24/7 operation.