Frequently Asked Questions

Brain Ultimate is the ONLY TMS system using pure deionized water cooling instead of transformer oil:

• Safety: Eliminates risks associated with transformer oil
• Efficiency: Operates continuously without cooling breaks
• Maintenance: 2–3 years between coolant service vs. complex oil changes
• Performance: Consistent treatment delivery all day long
• Cost: No per-pulse or per-use fees — most competitive pricing

Combined with Brain Ultimate Cloud connectivity and EB Neuro neurophysiology integration.

TMS is an FDA-cleared, non-invasive treatment using focused magnetic field pulses (up to 100 Hz) to stimulate targeted brain regions. Repeated sessions lead to lasting improvements in depression and other conditions.

FDA-cleared for MDD and OCD, with 176 peer-reviewed studies involving over 5,000 participants.

• TMS M-Series Device: Contact for pricing
• Brain Ultimate Cloud: $150/mo base (1 TMS + unlimited PCs); +$75/mo per additional TMS device. Annual: $1,650/year
• Installation: On-site $3,000 (1–2 days), Remote $1,200 (4–6 hours)
• Accessories: Positioning caps $150/10-pack, Ear plugs $27/10 pairs

Flexible financing available. Contact 888-570-2595 ext 801.

• Frequency: 0.1–100 Hz
• Intensity: 0–200% MT (software range), up to 100% system output
• Cooling: Proprietary deionized water (24/7)
• Protocols: 4 FDA-cleared (MDD 19-min, MDD 37-min, iTBS, OCD)
• Pulse Type: Biphasic
• Coil Lifespan: 20 million pulses
• Software: QuickStim v3.3.8+ with Cloud
• Safety: Dual-tier — 41°C warning + 42°C auto-stop
• Power: 230VAC/50Hz native; US requires step-down transformer, 3500W, 5 kVA min

Compatible with neuronavigation, EEG monitoring, and MEP module ($2,950 add-on).

HIPAA-compliant cloud platform for remote TMS management:

• Access: Via approved devices running QuickStim only
• Custom Shards: Each practice gets isolated AWS cloud environment
• Features: Automatic backups, practice analytics, protocol management
• Remote Support: Via SplashTop (not AnyDesk)

Pricing: $150/mo base (1 TMS device + unlimited PCs); +$75/mo per additional TMS device. Annual: $1,650/year. Setup: 2–3 business days.

• Figure-8 Liquid-Cooled (Flat): $6,000 — Standard MDD treatment
• Figure-8 Liquid-Cooled (Angulated): $6,000 — Enhanced positioning
• Liquid Double Cone Coil: $7,000 — OCD treatment
• Figure-8 Air-Cooled: $5,500

All liquid-cooled coils use proprietary deionized water for continuous operation. Each rated for 20 million pulses. Lightest figure-8 coil on the market.

• Minimum Room: 10' × 12' (120 sq ft)
• Power: 230VAC/50Hz native; US requires step-down transformer (included), 3500W draw, 5 kVA minimum dedicated circuit
• Operating Temp: 10–35°C
• Storage Temp: -20–60°C
• Included: Ergonomic chair, positioning arm, computer with software

• Daily: Visual inspection, startup verification
• Monthly: Cooling flow check, connection inspection
• Quarterly: System diagnostics, software updates
• Coolant: Deionized water — 2–3 years between replacement, refill at 85% capacity
• Annual: Capacitor testing, full calibration

24/7 technical support available via SplashTop.

FDA-cleared (K230735) for MDD and OCD. Additional cleared indications: Anxious Depression, Smoking Cessation, Migraine.

• Standard MDD: 19 min, 10Hz, 3000 pulses
• Enhanced MDD: 37 min, 10Hz, 3000 pulses
• iTBS: 3:12, 50Hz bursts, 600 pulses (K243460)
• OCD: 18 min, 20Hz, 2000 pulses (K243459)

1. Preparation (5 min): Seated in ergonomic treatment chair
2. Positioning (5 min): Coil positioned using positioning cap
3. Motor Threshold (15 min, first session): Optimal stimulation level determined
4. Treatment (3–37 min): Magnetic pulses per protocol
5. Completion: Resume normal activities immediately

Patients remain awake and alert. Tapping sensation and clicking sounds; earplugs provided.

• Frequency: 5 sessions/week
• Duration: 4–6 weeks
• Total: 20–30 sessions with optional maintenance taper

Session lengths: Standard MDD 19 min, Enhanced 37 min, iTBS 3:12, OCD 18 min.

Intermittent Theta Burst Stimulation — FDA-cleared (K243460):

• Duration: 3 minutes 12 seconds
• Efficacy: Comparable to 37-minute protocols
• Mechanism: 600 pulses in triplet bursts at 50Hz
• Throughput: 10+ patients/day possible

• Response Rate: 50–60%
• Remission Rate: 30–40%
• Treatment-Resistant: Effective after medication failures
• Durability: Benefits last 12+ months with maintenance

• Medications: Can continue antidepressants
• Psychotherapy: Excellent complement
• QEEG: Objective monitoring (assessment only — not treatment optimization)
• Neuronavigation: Precision targeting compatible

• FDA Clearance: K243459
• Protocol: 18 min, 20Hz, targeting supplementary motor area
• Duration: 6 weeks daily
• Response: 30–40% significant symptom reduction
• Coil: Liquid Double Cone ($7,000)

EB Neuro S.p.A. is Brain Ultimate's sister company — both operate under the Hanix United corporate family:

• Heritage: Founded early 1970s, 70+ years of Italian excellence
• Global: 50+ countries served
• FDA Cleared: All products FDA 510(k) cleared (K242305)
• Role: Brain Ultimate is authorized NA distributor

EEG: BE Plus PRO (22–128ch), BE Plus LTM (wireless, 272ch), BE Micro (72hr), BE Micro aEEG (NICU), Neurotravel Light (51ch, USB), ICU EEG-SEP.

EMG/EP: NeMus 1, NeMus 2, NExT Station.

Software: Galileo NT (unified, HL7/DICOM).

All FDA cleared. Contact 888-570-2595 ext 801.

Yes — all EB Neuro hardware and software are FDA 510(k) cleared under K242305 for clinical diagnostics, research, and long-term monitoring.

• Pre-Treatment: QEEG assessment (objective measurement only)
• During Treatment: Real-time EEG monitoring
• Post-Treatment: Objective outcome tracking
• MEP Module: $2,950 add-on
• Data: Galileo NT integration

Unified neurophysiology software (FDA cleared). Modules: EEG_NET, NExT (EMG/EP), GALAXY_Sleep, ICU. Microsoft SQL database, HL7/DICOM integration, BESA/Persyst/LORETA compatible.

24/7 technical support, operator training, professional installation, service/calibration packages. Contact 888-570-2595 ext 801 or support@brainultimate.com.

• Function: Objective brain activity measurement
• Application: Assessment tool ONLY — not for optimization or protocol selection
• Compatibility: Works with ANY TMS brand
• Caps: Standard cloth caps with positioning marks (not LED caps)

• Neurotravel Light: 51ch, USB powered, portable — ideal for TMS practices
• BE Plus PRO: 22–128ch, research-grade
• BE Micro: 19–21ch, 72hr ambulatory

All use standard cloth positioning caps.

EEG: Raw brain electrical activity, visual interpretation, qualitative.

QEEG: Statistical analysis of EEG data, normative database comparison, objective quantitative measurements.

Both are assessment tools — neither provides treatment recommendations.

No — TMS works effectively without QEEG. Optional benefits: objective baseline measurements, outcome tracking, research value, practice differentiation.

Quote-based pricing. All FDA cleared (K242305). Contact 888-570-2595 ext 801.

Included with installation at no additional cost:

• On-Site ($3,000): 1–2 days hands-on training
• Remote ($1,200): 4–6 hours virtual training
• Topics: Device operation, safety, protocols, motor threshold, QuickStim, troubleshooting, patient positioning
• Ongoing: 24/7 technical support

Through Metro NeuroHealth (not sold by Brain Ultimate):

• Scale Up ($3,799): Forms, billing setup, 2 training courses
• Accelerator ($6,300): Scale Up + credentialing for 8 payer networks + rate negotiations
• Add'l Credentialing: $329/application

1. Schedule a demo
2. Receive customized quote
3. Choose setup package (optional)
4. Place order
5. Installation & training (1–2 days on-site or 4–6 hours remote)
6. Launch — start treating patients

Timeline: 4–6 weeks from order. Contact 888-570-2595 ext 801.

• Reimbursement: $300–500/session
• Volume: 8–12 patients/day with 24/7 cooling
• Course: 20–30 sessions/patient
• Annual Revenue: $500K–$1M+ per device

• Consumables: Caps $150/10-pack, ear plugs $27/10 pairs
• Maintenance: 2–3 years between coolant replacement (deionized water)
• Optional: Brain Ultimate Cloud $150/mo base + $75/mo per additional device
• No Per-Pulse Fees: Lower ongoing costs than competitors

Yes — multiple financing partners, professional net terms, lease options, trade-in discussions. No per-pulse fees. Contact 888-570-2595 ext 801.

• Highest IF: 10.7
• High-Impact: 24 publications with IF ≥ 4.0
• Participants: 5,000+
• Categories: 30+ research areas

By condition: Stroke 53, Theses 37, Depression 16, Pain 13, Other 57.

• M-100 Platform: 96 studies specifically using M-100
• Related Devices: 80 studies using other devices
• Journal Quality: IF up to 10.7
• Geography: 50+ countries

Yes — 150+ institutional partnerships, regular conference presence (APA, CTMS, SfN, OHBM), supporting studies in stroke, pain, and other conditions.

Visit brainultimate.com/research, PubMed, or Google Scholar. Look for studies with IF ≥ 4.0 for highest quality.

Common (mild): Scalp discomfort, mild headache, facial twitching, lightheadedness (rare).

Rare (<0.1%): Seizures, temporary hearing issues without earplugs.

NOT experienced: No weight gain, sexual dysfunction, sedation, cognitive impairment, GI issues, or systemic side effects.

Absolute Contraindications: Aneurysm clips/coils, neck/brain stents, deep brain stimulators, cochlear implants, metallic ear/eye implants, shrapnel in head/neck, facial tattoos with metallic ink.

Generally Safe: Dental fillings, braces, titanium skull plates (discuss with physician). Always use standardized TMS safety checklist.

FDA Clearances: MDD (K230735), OCD (K243459), iTBS (K243460).

Insurance: Medicare, BCBS, Aetna, Cigna, UHC, Humana, many regional plans. Requirements: MDD diagnosis, 2–4 failed antidepressant trials, moderate-to-severe symptoms, medical necessity documentation.

• Thermal Protection: Dual-tier — 41°C warning alert + 42°C automatic shutdown
• Emergency Stop: Immediate cessation
• Cooling: Proprietary deionized water (eliminates oil/shock risks)
• Software: QuickStim protocol safety limits
• Coil Tracking: 20M pulse lifespan monitoring
• Positioning: Secure system prevents movement

6 global certifications: FDA, CE, TGA, KFDA, NMPA, CFDA Class III.

• USA: FDA (K230735, K243459, K243460)
• Europe: CE Mark & MDR
• Australia: TGA
• South Korea: KFDA
• China: NMPA/CFDA Class III

Active in 50+ countries.