TMS Protocols for MDD
19-minute Protocol
This protocol is performed at 120% of motor threshold. The train(s) consist of 40 pulses: 10 pulses a second for a total of 4 seconds, followed by a break of 11.0 seconds. This is repeated 75 times. The total duration is 18 minutes 26 seconds, and the total number of pulses is 3000.
| Parameters | Values |
|---|---|
| Stimulation type | Biphasic |
| Stimulus amplitude (% of MT) | 120 |
| Pulse frequency in train (Hz) | 10 |
| Pulses in train | 40 |
| Number of trains | 75 |
| Intertrain interval(s) | 11.0 |
| Total time | 00:18:26 |
| Total pulses | 3000 |
37-minute Protocol
| Parameters | Values |
|---|---|
| Magnetic field intensity | 120% of the MT |
| Frequency | 10 Hz |
| Train duration | 4 sec |
| Inter-train interval | 26 sec |
| Number of trains | 75 |
| Magnetic pulses per session | 3000 |
| Treatment session duration | ~37.0 min |
| Sessions/wk | 5 |
| Treatment schedule | 5 daily sessions for 6 weeks |
| Area of brain to be stimulated | Left Dorsolateral Prefrontal Cortex |